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Gonadorelin

Gonadorelin

Section 8 of Luojia Village, Fuyi Road, Dalong Street, Panyu District, Guangzhou – 广州 – 中国,广东18102676775Facebook
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起始
广州.
目的地
欧洲联盟.
50 Crossings是一切
广州 (中国,广东) - 安德莱赫特 (比利时)广州 (中国,广东) - 布尔诺 (捷克共和国)
广州 (中国,广东) - 格拉茨 (奥地利)广州 (中国,广东) - 利马索尔区 (塞浦路斯)
广州 (中国,广东) - 奥尔堡 (丹麦)广州 (中国,广东) - 杜布羅夫尼克 (克罗地亚)
广州 (中国,广东) - 布尔加斯 (保加利亚)
描述

1. Quick Details:

Product name: Gonadorelin
Synonyms: GnRH; Gonadotropin-Releasing Hormone; LHRH; Luliberin; Luteinizing Hormone-Releasing Factor
Unit size: 2 mg/vial & 10mg/vial
Cas No: 71447-49-9
Sequence: p-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 acetate salt
Purity: ≥99% (HPLC)
Physical State: Lyophilized Powder
Solubility: Soluble in water or 1% acetic acid
Usage: Gonadorelin, also known as GnRH or LHRH, is produced by neuroendocrine cells within the hypothalamus. The hormone is secreted pulsatilely. Gonadorelin induces the release of LH and FSH from the anterior pituitary. After a transient increase, continuous administration of gonadorelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.


Applications:
Mainly has a strong angiotensin II vasoconstriction and increase in blood pressure. The mechanism is:
1. So that the body arteriole smooth muscle contraction, increased peripheral resistance;
2. So increase the release of adrenal aldosterone, causing sodium retention, increased blood volume;
3. Directly contribute to renal tubular sodium and water reabsorption;
4. So the brain central nervous sympathetic vasoconstrictor activity, causing increased peripheral vascular resistance;
5. Stimulate the adrenal medulla to release epinephrine and norepinephrine

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